Proflavin Acrilin Ointment

Proflavin Acrilin Ointment

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  • Proflavine Hemisulfate is the hemisulfate salt form of proflavine, and acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and antiseptic purposes.
  • Upon topical application of proflavinehemisulfate, proflavine diffuses into cells intercalates into DNA, thereby accumulating in and staining the nucleus.
  • Duringfluorescence imaging, the cell nuclei can be visualized.
  • This allows nuclear morphometry and the identification of cancer cells.
  • In addition, proflavine exerts its antibacterial effect by binding to bacterial DNA,therebydisruptingDNAsynthesis and halting bacterial cell growth.  

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